Description
Product Characteristics: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of LTBP1 in mouse serum, plasma, tissue homogenates, cell lysates, cell culture supernates.
Target Information: The protein encoded by this gene belongs to the family of latent TGF-beta binding proteins (LTBPs). The secretion and activation of TGF-betas is regulated by their association with latency-associated proteins and with latent TGF-beta binding proteins. The product of this gene targets latent complexes of transforming growth factor beta to the extracellular matrix, where the latent cytokine is subsequently activated by several different mechanisms. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]